PATTERN REGULATION IN AUTOGRAFTS OFHYDRA OLIGACTIS: POSITIONAL VALUES AND DIFFUSABLE MORPHOGENS
نویسندگان
چکیده
منابع مشابه
Morphogens, their identification and regulation.
During the course of development, cells of many tissues differentiate according to the positional information that is set by the concentration gradients of morphogens. Morphogens are signaling molecules that emanate from a restricted region of a tissue and spread away from their source to form a concentration gradient. As the fate of each cell in the field depends on the concentration of the mo...
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Concentration gradients of small diffusible molecules called morphogens are key regulators of development, specifying position during pattern formation in the embryo. It is now becoming clear that additional or alternative mechanisms involving interactions among cells are also crucial for positional specification.
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One of the earliest and most-fundamental pattern- formation events in embryonic development is endoderm and mesoderm specification. In sea urchin embryos, this process begins with blimp1 and wnt8 gene expression at the vegetal pole as soon as embryonic transcription begins. Shortly afterwards, wnt8/blimp1 expression spreads to the adjacent ring of mesoderm progenitor cells and is extinguished i...
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Certain key enzymes of alternative pathways of glucose metabolism, of amino acid metabolism and of redox systems have been measured in hydra and this profile compared with mammalian differentiated tissues with a view to locating pathways of specific importance in hydra. There was a marked constant proportionality in the major part of the enzymes investigated, the profile suggested a metabolic p...
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Peter A. Lawrence* and Gary Struhl† Epigenesis, at least in Drosophila, depends on three steps which interlock and overlap; we simplify and refer *Medical Research Council Laboratory of Molecular Biology to these as the “central dogma.” First, positional information in the form of morphogen gradients allocates Hills Road Cambridge CB2 2QH cells into nonoverlapping sets, each set founding a comp...
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ژورنال
عنوان ژورنال: The Biological Bulletin
سال: 1984
ISSN: 0006-3185,1939-8697
DOI: 10.2307/1541229